Migraine

Last updated: April 18, 2022
Sponsor: Eli Lilly and Company
Overall Status: Active - Recruiting

Phase

4

Condition

Migraine (Adult)

Treatment

N/A

Clinical Study ID

TX290680
I5Q-MC-CGBD
  • Ages 18-65
  • All Genders

Study Summary

The purpose of this study is to assess whether galcanezumab is superior to rimegepant in the prevention of migraine in participants with episodic migraine. The study duration will be approximately 6 months.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18 to 65 Years
  • Have a diagnosis of migraine, with or without aura, as determined by the study investigator and in consideration of International Headache Society International Classification of Headache Disorders - 3rd edition guidelines (ICHD-3 2018)

Exclusion

Exclusion Criteria:

  • Have a known hypersensitivity to rimegepant or galcanezumab, and their excipients, or to multiple drugs, monoclonal antibodies or other therapeutic proteins
  • Have acute cardiovascular events and/or serious cardiovascular risk, or have had myocardial infarction, unstable angina, percutaneous coronary intervention, coronary artery bypass graft, or stroke within 6 months of screening, or have planned cardiovascular surgery or percutaneous coronary angioplasty.
  • Evidence of significant active or unstable psychiatric disease by medical history, such as bipolar disorder, schizophrenia, personality disorders, or other serious mood or anxiety disorders.
  • Women who are pregnant or nursing
  • Current use or prior exposure to any calcitonin gene related peptide (CGRP) antagonist (small molecule or antibody) for any indication, including those who have previously completed or withdrawn from this study or any other study investigating a CGRP antagonist (small molecule or antibody

Study Design

Study Start date:
Estimated Completion Date:

Study Description

  • Condition: Migraine
  • Clinical Trial Identifier: NCT05127486
  • Sponsor: Eli Lilly and Company

Looking for participants within a 35 mile radius of the study site.

Connect with a study center

  • Clinical Research Consortium

    Las Vegas, Nevada 89119
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.