Real-world Study on the Prevention of Neutropenia After Tumor Treatment With Mecapegfilgrastim Injection

Last updated: February 24, 2026
Sponsor: Hebei Medical University Fourth Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neutropenia

Treatment

Mecapegfilgrastim Injection

Clinical Study ID

NCT07434063
HBAD-FN-ZLZH001
  • Ages > 18
  • All Genders

Study Summary

This study is a multicenter, observational real-world study, aiming to observe and evaluate the efficacy and safety of prophylactic application of Mecapegfilgrastim Injection in tumor patients after radiotherapy/chemotherapy/immunotherapy in the real world to prevent neutropenia.The subjects who met the inclusion criteria of the protocol were defined as those who needed radiotherapy/chemotherapy/immunotherapy after being diagnosed with solid malignant tumors. The researchers believed that the subjects needed to use Mecapegfilgrastim Injection for primary/secondary prevention after receiving tumor treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

    1. Patients with malignant tumors confirmed by histopathology or cytology; 2. Age ≥18 years old; 3. After referring to various guidelines, the researchers believedthat the subjects:
  1. Patients who are currently receiving treatment regimens with high FN risk;

  2. Patients who are currently receiving treatment regimens for moderate FN riskand meet any one of the factors that increase the risk coefficient;

  3. FN or dose-limiting neutropenia events have occurred in previous treatmentcycles;

  4. In addition to the above, the researchers believe that the medication regimenswill cause neutropenia and affect the normal treatment of the subjects; 4.Researchers believe that they can benefit; 5. Voluntarily participate in thisclinical trial and be able to sign the informed consent form in person.

Exclusion

Exclusion Criteria:

    1. Those who are allergic to the test drug; 2. Those with mental or neurologicaldisorders who are unable to cooperate; 3. Pregnant or lactating female patients;Women of childbearing age who refuse to take contraceptive measures; 4. Those whowere considered unsuitable for inclusion by the researchers.

Study Design

Total Participants: 200
Treatment Group(s): 1
Primary Treatment: Mecapegfilgrastim Injection
Phase:
Study Start date:
June 18, 2025
Estimated Completion Date:
June 30, 2027

Connect with a study center

  • HebeiMuFH

    Shijiazhuang 1795270, Hebei 1808773
    China

    Active - Recruiting

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