Phase
Condition
Obesity
Diabetes Prevention
Hypertriglyceridemia
Treatment
UBT251
Placebo
Clinical Study ID
Ages 18-65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Male or female (sex at birth).
For Part C: Japanese, Chinese or non-Asian participants (all self-reported):
For Japanese participants: both parents of Japanese descent.
For Chinese participants: both parents of Chinese descent.
For non-Asian participants: both parents of non-Asian descent (non-Asian isdefined as of countries outside of Asia).
Age at the time of signing the informed consent:
For Part A: 18-55 years (both inclusive)
For Part B: 18-65 years (both inclusive)
For Part C: 18-55 years (both inclusive).
BMI at screening (overweight and obesity should be due to excess adipose tissue, asjudged by the investigator):
For Part A: 27.0-39.9 kilogram per meter square (kg/m^2) (both inclusive)
For Part B: 30.0-50.0 kg/m^2 (both inclusive)
For Part C: 24-34.9 kg/m^2 (both inclusive)
Considered eligible based on the medical history, physical examination, and theresults of vital signs, electrocardiogram (ECG), and clinical laboratory testsperformed during the screening visit, as judged by the investigator.
Exclusion
Exclusion Criteria:
Known or suspected hypersensitivity to study intervention(s) or related products.
Treatment with any marketed product containing compounds with glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) or glucagon receptoragonism within 90 days before screening.
Any condition, unwillingness or inability, which in the investigator's opinion mightjeopardise the participant's safety or compliance with the protocol.
Study Design
Connect with a study center
Altasciences Clinical Company, Inc
Montreal, Quebec H3P 3P1
CanadaActive - Recruiting
Altasciences Clinical Company, Inc
Montreal 6077243, Quebec 6115047 H3P 3P1
CanadaSite Not Available
Altasciences Clinical LA, Inc.
Cypress, California 90630
United StatesActive - Recruiting
Altasciences Clinical LA, Inc.
Cypress 5341256, California 5332921 90630
United StatesSite Not Available
Altasciences Clinical Kansas, Inc.
Overland Park, Kansas 66212
United StatesActive - Recruiting
Altasciences Clinical Kansas, Inc.
Overland Park 4276873, Kansas 4273857 66212
United StatesSite Not Available

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