Broccoli Sprout Extract for Cognitive Function

Inclusion Criteria:

• Age: Adults aged 55-85 years (inclusive), both male and female

• Global Deterioration Scale (GDS) score of 2-3:

GDS 2: Subjective memory impairment without objective evidence GDS 3: Mild objective memory impairment

• Absence of dementia according to established diagnostic criteria

• Ability to read Korean

Exclusion Criteria:

• Severe medical conditions within the past 6 months: History of severecerebrovascular disease (cerebral infarction, cerebral hemorrhage), cardiac disease (angina, myocardial infarction, heart failure, arrhythmia requiring treatment), ormalignancy (Note: Participants with a history of cerebrovascular or cardiac diseasewho are clinically stable may be included at the investigator's discretion)

• Cognitive impairment-associated diseases: Dementia, Parkinson's disease, cerebralinfarction, or other conditions associated with cognitive decline Uncontrolledhypertension: Blood pressure ≥160/100 mmHg (measured after 10 minutes of rest)

• Poor glycemic control: Fasting blood glucose ≥160 mg/dL in diabetic patients

• Uncontrolled thyroid dysfunction: Currently receiving treatment for uncontrolledhypothyroidism or hyperthyroidism

• Renal impairment: Serum creatinine ≥2 times the upper limit of normal for theinstitution

• Hepatic impairment: AST or ALT ≥2 times the upper limit of normal for theinstitution

• Severe gastrointestinal symptoms: Complaints of severe heartburn, dyspepsia, orother gastrointestinal distress

• Medications affecting cognitive function within the past month: Use of drugs (antipsychotics, anti-degenerative agents, cognitive enhancers, tricyclicantidepressants, hormone replacement therapy) or health functional foods that mayinfluence cognitive function due to dementia or other cognitive abnormalities

• Other clinical trial participation: Participation in other drug clinical trialswithin the past month or planned participation during the study period

• Alcohol use disorder, severe

• Food allergies: Known allergic reactions to study product components

• Investigator discretion: Any other condition deemed inappropriate for studyparticipation by the investigator