Multilevel Determinants of Socioeconomic Disparities in Geographic Late-Stage Hepatocellular Carcinoma Hotspots

Last updated: January 28, 2026
Sponsor: University of Southern California
Overall Status: Active - Recruiting

Phase

N/A

Condition

Digestive System Neoplasms

Liver Disorders

Abdominal Cancer

Treatment

Non-Interventional Study

Clinical Study ID

NCT07312162
19PS-21-7
K23MD016963
19PS-21-7
P30CA014089
NCI-2024-03737
  • Ages > 18
  • All Genders

Study Summary

This study evaluates barriers to early detection of liver cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

    • Adults (18+)

  • New diagnosis of HCC

  • Able to provide informed consent

Additional criteria:

  • Must complete survey

  • Residential address in a late stage hotspot

  • Medicaid insurance or uninsured

  • English, Spanish and Chinese speakers

Exclusion

Exclusion Criteria:

    • Residence outside of Los Angeles County

  • Non-HCC liver tumors

  • Incarcerated patients

  • Pregnant women

Study Design

Total Participants: 730
Treatment Group(s): 1
Primary Treatment: Non-Interventional Study
Phase:
Study Start date:
January 01, 2022
Estimated Completion Date:
December 31, 2027

Study Description

PRIMARY OBJECTIVES:

I. To identify individual-level social and clinical determinants of socioeconomic disparities in late stage Hepatocellular Carcinoma (HCC) burden with a prospective survey of patients with incident HCC. II. To qualitatively explore the multilevel barriers to completion of the early detection pathway for HCC in low socioeconomic status (SES) populations.

OUTLINE: This is an observational study.

Participants complete surveys, have their medical records reviewed, and may complete an interview on study.

Connect with a study center

  • USC / Norris Comprehensive Cancer Center

    Los Angeles 5368361, California 5332921 90033
    United States

    Active - Recruiting

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