A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

Inclusion Criteria:

• Have recently quit smoking and are motivated to stay quit from smoking

• Are reliable and willing to make themselves available for the duration of the studyand attend required study visits and are willing and able to follow study proceduresas required, such as self-inject study intervention

Exclusion Criteria:

• Have evidence of any substance use disorder within the past 180 days prior toscreening, except mild alcohol use disorder, mild cannabis use disorder, or tobaccouse disorder

• Have answered "yes" to either Question 4 or Question 5 on the "Suicidal Ideation"portion of the C-SSRS and the ideation occurred within the past 6 months, or haveanswered "yes" to any of the suicide-related behaviors on the "Suicidal Behavior"portion of the C-SSRS and the behavior occurred within the past 6 months

• Have severe chronic obstructive pulmonary disease, or any other clinically severerespiratory condition that in the investigator's opinion may pose a risk.

• Have participated in a clinical study and have received active treatment, or unknownif they received active treatment, within 90 days or 5 half-lives (whichever islonger) before screening