Evaluation of a Neural-Controlled Powered Prosthesis Across Diverse Real-World Tasks

Last updated: September 24, 2025
Sponsor: Massachusetts Institute of Technology
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

MIT Powered Leg

Clinical Study ID

NCT07204912
2503001589
  • Ages 18-70
  • All Genders

Study Summary

The purpose of this study is to evaluate the performance and adaptability of a neural-controlled powered knee or ankle prosthesis across diverse real-world mobility tasks. This research aims to assess how compare the sense of embodiment with the device, symmetry, and stability of a person with an lower-extremity amputation walking with a bionic prosthesis and their prescribed prosthesis. Findings from this study will inform future developments in bionic prosthesis design with optimal integration with the human body, with the goal of improving prosthetic integration into daily life.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male or Female age 18-70.

  • The patient must have a unilateral transfemoral amputation .

  • The patient must have the ability to ambulate at variable cadence (an expected lowerextremity prosthesis functional level of K3 or above).

  • The patient must have adequate socket to support the device.

Exclusion

Exclusion Criteria:

  • Women who are pregnant.

  • Severe co morbidity, atypical skeletal anatomy, or poor general physical/mentalhealth that, in the opinion of the Investigator, will not allow the subject to be agood study candidate (i.e. other disease processes, mental capacity, substanceabuse, shortened life expectancy, vulnerable patient population, BMI >40, etc.).

Study Design

Total Participants: 10
Treatment Group(s): 1
Primary Treatment: MIT Powered Leg
Phase:
Study Start date:
May 31, 2025
Estimated Completion Date:
May 31, 2028

Connect with a study center

  • MIT Media Lab

    Cambridge 4931972, Massachusetts 6254926 02139
    United States

    Active - Recruiting

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