Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

Last updated: January 27, 2026
Sponsor: City of Hope Medical Center
Overall Status: Active - Recruiting

Phase

3

Condition

Hematologic Neoplasms

Treatment

Standard of Care Arm (Enhanced usual care)

Questionnaire Administration

Best Practice

Clinical Study ID

NCT07186192
25328
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The overall purpose of this randomized control trial (RCT) is to determine the clinical effect of a multilevel, RPM-enhanced intervention during and after completion of outpatient CAR-T therapy in 190 patients and their family caregivers (FCGs).

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patient Inclusion Criteria Informed Consent and Willingness to Participate

  1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria

  2. Age ≥ 18 years old at the time of enrollment

  3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria

  4. Relapsed or refractory hematologic malignancy

  5. Scheduled to receive outpatient standard of care (SOC) CAR-T therapy

  6. Has a FCG committed to living with the patient for the duration of the study

Family Caregiver Inclusion Criteria Informed Consent and Willingness to Participate

  1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria

  2. Age ≥ 18 years old at the time of enrollment

  3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria

  4. Family member or friend identified by the patient and defined as a person who knows the patient well and is involved in the patient's medical care

Exclusion Criteria 1. An employee who is under the direct/indirect supervision of the PI/ a co-investigator/ the study manager 2. A direct study team member

Study Design

Total Participants: 190
Treatment Group(s): 6
Primary Treatment: Standard of Care Arm (Enhanced usual care)
Phase: 3
Study Start date:
January 14, 2026
Estimated Completion Date:
March 29, 2029

Connect with a study center

  • City of Hope Medical Center

    Duarte 5344147, California 5332921 91010
    United States

    Active - Recruiting

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