Phase
Condition
Diabetes Prevention
Hypertriglyceridemia
Obesity
Treatment
NNC0662-0419
Clinical Study ID
Ages 18-55 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Male or female (sex at birth) Japanese, Chinese or non-Asian participants (allself-reported).
For Japanese participants: both parents of Japanese descent.
For Chinese participants: both parents of Chinese descent.
For non-Asian participants: both parents of non-Asian descent (non-Asian isdefined as of countries outside of Asia).
Age 18-55 years (both inclusive) at the time of signing the informed consent.
Body mass index (BMI) between 24.0 and 34.9 kilogram per square meter (kg/m^2) (bothinclusive) at screening. Overweight should be due to excess adipose tissue, asjudged by the investigator.
Considered eligible based on the medical history, physical examination, and theresults of vital signs, electrocardiogram and clinical laboratory tests performedduring the screening visit, as judged by the investigator.
Exclusion
Exclusion Criteria:
Known a* or suspected hypersensitivity to study intervention(s) or related products.
Any disorder, unwillingness or inability which in the investigator's opinion, mightjeopardise the participant's safety or compliance with the protocol.
2nd or 3rd degree atrioventricular-block, prolongation of the QRS complex over 120millisecond (msec), or of the corrected QT interval by Fridericia (QTcF) calculationover 450 msec (females) or 430 msec (males), or any other clinically significantabnormal electrocardiogram (ECG) results as judged by the investigator, atscreening.
Glycated haemoglobin (HbA1c) greater than or equal to >= 6.5percent (%) (48millimoles per liter [mmol/mol]) at screening.
Calcitonin >= 50 nanogram per liter (ng/L) at screening. a* - As declared by theparticipant or reported in the medical records.
Study Design
Connect with a study center
Altasciences Clinical LA, Inc.
Cypress, California 90630
United StatesActive - Recruiting

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