A Real-World Study About Anemia in Chronic Kidney Disease in China(DASHENG)

Last updated: July 31, 2025
Sponsor: Wei Chen
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Anemia

Treatment

N/A

Clinical Study ID

NCT07098416
IIT-2025-121
  • Ages > 18
  • All Genders

Study Summary

Anemia affects the quality of life of CKD patients and increases the risk of CKD progression. we conducted a real-world study on patients with anemia in CKD to analyze the disease characteristics and treatment in Chinese patients with CKD-anemia.

Eligibility Criteria

Inclusion

Inclusion Criteria: CKD patients will be defined as those meeting any of the following criteria during the observation period:

  1. diagnosis of CKD (e.g., "%chronic kidney disease%", "%chronic nephropathy%", "%renalfailure%", "%nephritis%" for complete ICD-9/10 code mapping*)

  2. record of hemodialysis (HD) or peritoneal dialysis (PD) (refer to Attachment 2 fordialysis identification algorithms)

  3. ≥2 eGFR measurements <60 mL/min/1.73m² (calculated using CKD-EPI equation) with ≥3-month interval (excluding acute kidney injury)

Exclusion

Exclusion Criteria:

  1. Non-renal anemia due to trauma, traffic accidents, major hemorrhage, or otherconfirmed etiologies (e.g., acute hemorrhagic anemia, nutritional deficiency anemia,hemolytic anemia);

  2. Diagnosis of acute kidney disease (AKD) without chronic kidney disease (CKD)comorbidity;

  3. Incomplete critical data elements (including age, sex, or visit dates).

Study Design

Total Participants: 20000
Study Start date:
August 01, 2025
Estimated Completion Date:
August 31, 2027

Study Description

Anemia adversely affects the quality of life of CKD patients and increases the risk of CKD progression.

This study utilize data from approximately 20 medical centers across China. It aims to:

  1. Analyze the disease characteristics, current diagnostic and treatments in Chinese patients with CKD-anemia.

  2. Evaluate the safety and efficacy profiles of different drugs used for CKD-anemia.

  3. Explore the direct medical costs associated with CKD-anemia management within real-world clinical practice in China.

Connect with a study center

  • First Affiliated Hospital, Sun Yat-Sen University

    Guangzhou, Guangdong 510080
    China

    Site Not Available

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