R.E.C.K vs Exparel in Robotic Nephrectomy

Inclusion Criteria:

1. Ability to understand and willingness to sign an IRB-approved informed consent

2. Age ≥ 18 years at the time of consent.

3. Planned robotic partial or radical nephrectomy

Exclusion Criteria:

1. Determined not to be a candidate to receive R.E.C.K or Exparel per the enrollinginvestigator

2. Known pregnancy

3. Chronic opioid use within 30 days (as per patient report) prior to randomization (defined as ≥ 30 MME/day)

4. Uncontrolled intercurrent illness including, but not limited to, ongoing or activeinfection, symptomatic congestive heart failure, unstable angina pectoris, cardiacarrhythmia, or psychiatric illness/social situations that would limit compliancewith study requirements as determined by the investigator.

5. Known allergy to R.E.C.K. and/or Exparel