Phase
Condition
Lymphoproliferative Disorders
Blood Clots
Chemotherapy
Treatment
KLN-1010
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Participants must have relapsed and refractory multiple myeloma (RRMM) withmeasurable disease
Participants must have received at least 3 prior lines of therapy including aproteasome inhibitor (PI), an immunomodulatory drug (IMiD), and CD38-directedmonoclonal antibody
Participants must have an Eastern Cooperative Group (ECOG) performance status of 0-1
Participants must have acceptable laboratory values as defined by the protocol
Exclusion
Exclusion Criteria:
Participants must not have known central nervous system (CNS) involvement withmyeloma
Participants cannot have plasma cell leukemia, Waldenstrom's macroglobulinemia,POEMS (polyneuropathy, organomegaly, endocrinopathy, and skin changes) syndrome, orprimary light chain amyloidosis
Participants cannot have ongoing acute systemic infection requiring antimicrobialtherapy
Participants cannot require systemic steroids for any condition
Study Design
Connect with a study center
The Royal Prince Alfred
Camperdown, New South Wales 2050
AustraliaActive - Recruiting
The Royal Prince Alfred
Camperdown 2172563, New South Wales 2155400 2050
AustraliaSite Not Available
Peter MacCallum Cancer Centre
Melbourne, Victoria 3000
AustraliaActive - Recruiting
The Alfred Paula Fox Melanoma and Cancer Centre
Melbourne, Victoria 3004
AustraliaActive - Recruiting
Peter MacCallum Cancer Centre
Melbourne 2158177, Victoria 2145234 3000
AustraliaSite Not Available
The Alfred Paula Fox Melanoma and Cancer Centre
Melbourne 2158177, Victoria 2145234 3004
AustraliaActive - Recruiting
City of Hope
Duarte, California 91010
United StatesActive - Recruiting
Stanford University
Palo Alto, California 94304
United StatesActive - Recruiting
Emory University Hospital
Atlanta, Georgia 30322
United StatesActive - Recruiting
Providence Portland Medical Center
Portland, Oregon 97213
United StatesActive - Recruiting

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