Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia

Last updated: February 18, 2026
Sponsor: Comenius University
Overall Status: Completed

Phase

N/A

Condition

Stress

Depression

Emotional Processing

Treatment

N/A

Clinical Study ID

NCT07070180
APVV-22-0160
  • Ages 18-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study aims to investigate the links between psychological and biological immunity from the perspective of psychology, epidemiology, and immunology in a general population study sample as well as in a specific group of people in treatment for alcohol addiction.

Eligibility Criteria

Inclusion

Inclusion Criteria for 'General Slovak Population Sample':

  • Age between 18 - 50 years

  • Residency in the respective region for at least five years

  • Consent to participate in the study

Exclusion Criteria for 'General Slovak Population Sample':

  • Individuals younger than 18 or older than 50 years

  • Ongoing acute infectious disease on the day of testing

  • Eligible individuals who do not provide informed consent

Inclusion Criteria for the sample 'Individuals receiving inpatient treatment for alcohol addiction at the treatment facility':

  • Age between 18 - 50 years

  • Admission to treatment for alcohol addiction

  • Consent to participate in the study, Treatment completion

Exclusion Criteria for the sample 'Individuals receiving inpatient treatment for alcohol addiction at the treatment facility':

  • Individuals younger than 18 or older than 50 years

  • Eligible individuals who do not provide informed consent

  • Drop-out from alcohol addiction treatment

Study Design

Total Participants: 700
Study Start date:
January 01, 2024
Estimated Completion Date:
December 15, 2025

Study Description

The study will explore the associations between the level of psychological immunity and the current psychological state of the participants, possible links between the level of psychological immunity in adulthood and adverse childhood experiences, and finally, the association between the psychological immunity and biological immunity expressed by the self- assessed perceived immune status and on a molecular level by quantity of cytokines and in a specific subgroup also by natural killer cells. All this will be studied in a sample of general population as well as in a specific group of people in treatment for alcohol addiction that was chosen based on the known adverse immune-related health effects of excessive alcohol consumption.

Connect with a study center

  • Comenius University Bratislava, Faculty of Arts

    Bratislava, 81102
    Slovakia

    Site Not Available

  • Comenius University, Faculty of Medicine in Bratislava

    Bratislava, 81108
    Slovakia

    Site Not Available

  • Slovak Academy of Sciences, Institute of Neuroimmunology

    Bratislava, 84510
    Slovakia

    Site Not Available

  • Comenius University Bratislava, Faculty of Arts

    Bratislava 3060972, 81102
    Slovakia

    Site Not Available

  • Comenius University, Faculty of Medicine in Bratislava

    Bratislava 3060972, 81108
    Slovakia

    Site Not Available

  • Slovak Academy of Sciences, Institute of Neuroimmunology

    Bratislava 3060972, 84510
    Slovakia

    Site Not Available

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