Factors Influencing Bradycardia During Spinal Anesthesia in Obstetric Patients Undergoing Cesarean Section

Last updated: June 25, 2025
Sponsor: Superior University
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Heart Defect

Arrhythmia

Dysrhythmia

Treatment

N/A

Clinical Study ID

NCT07049705
MSAHSW/Batch-Fall23/916
  • Ages 18-40
  • All Genders

Study Summary

The study titled "Factors Influencing Bradycardia During Spinal Anaesthesia in Obstetric Patients Undergoing Caesarean Section"" aims to investigate the causes and patterns of bradycardia in pregnant women receiving spinal anesthesia during cesarean deliveries. Bradycardia, defined as a heart rate below 60 beats per minute, is a known complication of spinal anesthesia, often resulting from sympathetic blockade and unopposed parasympathetic activity. This condition may lead to hypotension, decreased cardiac output, and compromised fetal oxygenation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Obstetric patients aged 18-40 years.

  • Undergoing elective or emergency cesarean sections under spinal anesthesia.

  • Classified as ASA Physical Status I or II (relatively healthy or with mild systemicdisease).

  • Provided informed consent (either by the patient or legal guardian).

Exclusion

Exclusion Criteria:

  • Patients with pre-existing cardiac conditions (e.g., arrhythmias, conductionabnormalities).

  • Patients taking medications that affect heart rate, such as beta-blockers or calciumchannel blockers.

  • Patients with contraindications to spinal anesthesia (e.g., coagulopathy, infectionat the injection site).

  • Those undergoing combined spinal-epidural or general anesthesia.

  • Patients with incomplete medical records or unable to provide informed consent.

Study Design

Total Participants: 289
Study Start date:
March 17, 2025
Estimated Completion Date:
February 28, 2026

Study Description

The research seeks to enhance the understanding of both patient-specific and procedural risk factors, contributing to improved clinical management, safer anesthesia practices, and better maternal-fetal outcomes. Ethical approval and informed consent protocols are included to ensure participant safety and data confidentiality.

Connect with a study center

  • Maqsood Medical complex

    Peshawar, Khyber Pakhtunkhwa
    Pakistan

    Site Not Available

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