ICP-332 in Subjects With Non-segmental Vitiligo

Inclusion Criteria:

1. Male or female subjects aged ≥18 years and ≤75 years (Phase II portion). Male orfemale subjects ≥12 years of age and ≤75 years of age, adolescent subjects mustweigh ≥40 kg (Phase III portion).

2. Eligible subjects must meet all of the following criteria at screening and baseline:

3. The clinical diagnosis was non-segmental vitiligo for at least 3 months.

4. Involvement of BSA≥5%.

5. Facial involvement BSA≥0.5%.

6. F-VASI≥0.5 and T-VASI between 5 and 50.

7. Active or stable non-segmental vitiligo was present at both screening andbaseline visits.

8. Women of childbearing potential (WOCBP) and Men must agree to contraception.

9. Before beginning any screening or study specific procedures, subjects mustvoluntarily sign informed consent.

Exclusion Criteria:

1. Any of the following vitiligo related medical conditions and other skindiseases/conditions. a) Subjects had other types of vitiligo (including but not limited to segmentalvitiligo and mixed vitiligo) that did not meet the criteria for active or stablevitiligo described in Inclusion criteria 2.

2. History of any clinically major diseases, with the exception of vitiligo.

3. Pregnant or breastfeeding females.

4. The investigator considers that the subject is not suitable for participation inthis study for any reason.