Impact Of Early Cognitive Rehabilitation On Functional Outcomes Following Moderate Traumatic Brain Injury

Last updated: May 17, 2025
Sponsor: Amany Saadallah Hassan Mobarez
Overall Status: Active - Enrolling

Phase

N/A

Condition

Neurologic Disorders

Treatment

Control group

early cognitive therapy program in addition to selected physical therapy program (positioning, chest care exercise).

selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program

Clinical Study ID

NCT06981897
TBI
  • Ages > 18
  • All Genders

Study Summary

Purpose of the study:

This study aims to detect the impact of early cognitive rehabilitation on functional outcomes with patients following moderate traumatic brain injury.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Both Genders.

  2. Moderate traumatic brain injury patients will be included with GCS score 9-12.

  3. Patients' age 18 years old and more .

  4. All patients must be medically stable post trauma.

Exclusion

Exclusion Criteria:

  1. children under 18 years old .

  2. Previous cerebral infarction and intracranial space-occupying lesions.

  3. Patients with cancer and major underlying illnesses.

  4. Patients with diffuse axonal damage.

  5. Incomplete clinical and imaging data

  6. Patient with other neurological deficits or orthopedic abnormalities that causingdisability.

  7. Patients with serious psychiatric pathology or mentally. -

Study Design

Total Participants: 34
Treatment Group(s): 3
Primary Treatment: Control group
Phase:
Study Start date:
December 01, 2023
Estimated Completion Date:
July 01, 2025

Study Description

Intensive care unit (ICU) hospitalization saves lives but often costs ICU survivors, who often experience cognitive impairment and physical and functional disabilities. Early physical rehabilitation improves chances of regaining pre-hospital functional status, but early cognitive rehabilitation for these patients remains unexplored Traumatic brain injury occurs from violent blows or objects, causing physical and psychological effects. Signs may appear immediately or days later, affecting the brain's function and functioning . Traumatic Brain Injury (TBI) impacts health and quality of life, with unpredictable prognosis. Exercise is crucial for neuroplasticity and brain rewiring.The Glasgow Coma Scale, published in 1974, measures impaired consciousness in acute medical and trauma patients using eye-opening, motor, and verbal responses. It provides a clear, communicable picture of a patient's state.

The Rancho Los Amigos Scale (RLAS) is a medical assessment tool for individuals recovering from closed head injuries, including traumatic brain injuries. It evaluates cognitive and behavioral presentations as they emerge from coma, comparing patients' state of consciousness and reliance on assistance .

The Functional Independence Measure (FIM) is an 18-item assessment tool for evaluating patients' functional status in rehabilitation after stroke, traumatic brain injury, spinal cord injury, or cancer. It evaluates self-care, continence, mobility, transfers, communication, and cognition, with each item rated 1-7 .

Connect with a study center

  • Cairo University hospital

    Cairo,
    Egypt

    Site Not Available

  • Kasr Al-Ainy Emergency Hospital185

    Cairo, 11562
    Egypt

    Site Not Available

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