Study of BHV-1300 in Graves' Disease

Last updated: May 15, 2026
Sponsor: Biohaven Therapeutics Ltd.
Overall Status: Active - Recruiting

Phase

1

Condition

Thyroid Disorders

Thyroid Disease

Collagen Vascular Diseases

Treatment

BHV-1300

Clinical Study ID

NCT06980649
BHV1300-202
  • Ages 18-65
  • All Genders

Study Summary

The purpose of this study is to determine if BHV-1300 is a safe treatment in participants with Graves' Disease and to explore its effect on disease-specific biomarkers.

Eligibility Criteria

Inclusion

Key Inclusion Criteria:

  1. Participants must have serologically confirmed Graves' Disease.

Exclusion

Key Exclusion Criteria:

  1. History of hyperthyroidism not caused by Graves' Disease (e.g., toxic adenoma ortoxic multinodular goiter) and/or history of thyroid storm within six weeks of theBaseline visit.

  2. History of treatment with radioactive iodine or thyroid surgery.

Study Design

Total Participants: 15
Treatment Group(s): 1
Primary Treatment: BHV-1300
Phase: 1
Study Start date:
August 21, 2025
Estimated Completion Date:
September 30, 2027

Connect with a study center

  • Site-004

    Fitzroy, 3065
    Australia

    Active - Recruiting

  • Site-004

    Fitzroy 2166584, 3065
    Australia

    Site Not Available

  • Site-001

    Kotara, 2289
    Australia

    Active - Recruiting

  • Site-001

    Kotara 2161029, 2289
    Australia

    Site Not Available

  • Site-003

    Melbourne, 3128
    Australia

    Active - Recruiting

  • Site-003

    Melbourne 2158177, 3128
    Australia

    Site Not Available

  • Site-010

    Oaklands Park, 5046
    Australia

    Active - Recruiting

  • Site-010

    Oaklands Park 9973124, 5046
    Australia

    Site Not Available

  • Site-008

    Parkville, 3050
    Australia

    Active - Recruiting

  • Site-008

    Parkville 2153770, 3050
    Australia

    Site Not Available

  • Site-006

    St Leonards, 2065
    Australia

    Active - Recruiting

  • Site-006

    St Leonards 8029783, 2065
    Australia

    Site Not Available

  • Site-002

    Torquay, 3228
    Australia

    Active - Recruiting

  • Site-002

    Torquay 2146218, 3228
    Australia

    Site Not Available

  • Site-103

    South Gate, California 90280
    United States

    Active - Recruiting

  • Site-103

    South Gate 5397603, California 5332921 90280
    United States

    Site Not Available

  • Site-100

    Miami, Florida 33126
    United States

    Active - Recruiting

  • Site-100

    Miami 4164138, Florida 4155751 33126
    United States

    Site Not Available

  • Site-104

    Columbus, Georgia 31904
    United States

    Active - Recruiting

  • Site-104

    Columbus 4188985, Georgia 4197000 31904
    United States

    Site Not Available

  • Site-108

    Greenville, North Carolina 27834
    United States

    Active - Recruiting

  • Site-110

    Canton, Ohio 44718
    United States

    Active - Recruiting

  • Site-107

    Memphis, Tennessee 38119
    United States

    Active - Recruiting

  • Site-109

    Dallas, Texas 75246
    United States

    Site Not Available

  • Site-101

    Houston, Texas 77095
    United States

    Active - Recruiting

  • Site-106

    Houston, Texas 77054
    United States

    Active - Recruiting

  • Site-105

    Shavano Park, Texas 78231
    United States

    Active - Recruiting

  • Site-101

    Houston 4699066, Texas 4736286 77095
    United States

    Active - Recruiting

  • Site-106

    Houston 4699066, Texas 4736286 77054
    United States

    Site Not Available

  • Site-105

    Shavano Park 4728147, Texas 4736286 78231
    United States

    Site Not Available

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