Study of MT1013 Injection for the Treatment of Secondary Hyperparathyroidism (SHPT) Patients With Chronic Kidney Disease Undergoing Maintenance Dialysis

Inclusion Criteria:

1. Subject capable of understanding written information ,willing to participatein, and provide a written informed consent; 2.Male or female subjects must beat least 18 years old when signing the informed consent; 3.The subjects mustundergo maintenance hemodialysis three times a week or five times two weeks forat least three months； 4.Dialysate calcium concentration≥1.25 mmol/L (2.5mEq/L); 5.Diagnosed of Secondary Hyperparathyroidism (SHPT);

Exclusion Criteria:

• 1.Primary hyperparathyroidism; 2.Refusal to discontinue cinacalcet, etelcalcetide,or other calcimimetics during the study; 3.Has used RANKL inhibitors such asdenosumab within 6 months before screening. 4.Diagnosed with gastrointestinalbleeding within 6 months prior to screening; 5.Subjects with severe uncontrolledhypertension, defined as systolic blood pressure>180 mmHg and/or diastolic bloodpressure>110 mmHg, despite optimal drug treatment prior to enrollment; 6.Thesubjects underwent parathyroidectomy within 6 months prior to screening, or plan toundergo parathyroidectomy during the study; 7.Subjects are allergic or intolerant toany component of the investigational drug； 8.History of epileptic seizures orongoing epilepsy related treatment within 1 year prior to screening;