Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness

Inclusion Criteria:

1. Chinese, aged 12-19 years old;

2. Written informed assent/consent of participation into the study is given by theparticipant and his/her parent or guardian (for those aged under 18), respectively;

3. Having a DSM-5 diagnosis of unipolar non-seasonal depression as confirmed by theChinese version of the Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS) psychiatric interview, DSM-5 Seasonal specifier, AND having a score onChildren's Depression Rating Scale (CDRS-R) at least 40;

4. Being classified as evening chronotype according to the score on the reducedHorne-Östberg Morning-Eveningness Questionnaire (rMEQ), i.e. <12.

Exclusion Criteria:

1. A current diagnosis of substance abuse or dependence; a current or past history ofmanic or hypomanic episode, schizophrenia spectrum disorders, organic mentaldisorders, or intellectual disabilities;

2. Having a clinically significant suicidality (presence of suicidal ideation with aplan or an attempt) as assessed by K-SADS;

3. Having been enrolled in any other clinical trial investigational products within onemonth at the entry of the study;

4. Initiation of or change in antidepressant medication within past 4 weeks;

5. Having been or is currently receiving any structured psychotherapy;

6. With hearing or speech deficit;

7. Night shift worker;

8. Trans-meridian flight across at least two time zones in the past 3 months and duringthe study;

9. Presence of an eye disease, e.g., retinal blindness, severe cataract, glaucoma.