Effectiveness of Introducing Ultra-High B-Value Diffusion-Weighted Imaging as a Modified Abbreviated Protocol for Breast Cancer Detection

Last updated: May 6, 2025
Sponsor: Ain Shams University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carcinoma

Cancer/tumors

Treatment

N/A

Clinical Study ID

NCT06970288
MD45/2025
  • Ages 30-50
  • Female

Study Summary

The aim of this study is to evaluate the added value of non-contrast abbreviated MRI protocol featuring ultra-high B value Diffusion Weighted Imaging to detect, characterize suspicious breast lesions and avoid using contrast.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • • Women with suspicious breast mass (BIRADS 4a)

  • High risk women (Positive family history)

  • Women with suspicious axillary lymph nodes by Ultrasound

  • Women with dense breasts coming for MRI imaging.

Exclusion

Exclusion Criteria:

  • • Contraindications to MRI

  • Pacemaker, cochlear implant, claustrophobia, ocular implants

  • Contraindications to contrast administration:

  • Elevated kidney functions

  • Women who haven't undergone reliable Mammogram & Ultrasound

  • Women with prior treatment or intervention (e.g. biopsy)

  • Patients' refusal.

Study Design

Total Participants: 85
Study Start date:
May 10, 2025
Estimated Completion Date:
December 30, 2026

Connect with a study center

  • Ain Shams University

    Cairo, Abbasia
    Egypt

    Active - Recruiting

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