Phase
Condition
Anesthesia
Saliva And Salivary Gland Dysfunction
Treatment
lidocaine cream
Placebo
Clinical Study ID
Ages 18-60 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Aged 18 to 60 years;
With American Society of Anesthesiologists (ASA) physical status I or II;
Scheduled to undergo ophthalmic surgery following general anesthesia with LMA.
Exclusion
Exclusion Criteria:
Contraindications to LMA use;
A history of upper respiratory tract infection within one week prior to surgery;
Persistent pharyngeal symptoms (eg. throat irritation, dryness, or chronic cough,etc.) lasting ≥ 3 months;
Severe gastroesophageal reflux disease;
Morbid obesity, defined as a body mass index ≥ 40 kg/m2;
A predicted difficult airway (eg. a history of difficult airway, mouth opening < 3cm, Mallampati class 4, limited neck extension or cervical spine disease);
Presence of structural abnormalities, masses, infections, or scarring in the oralcavity or oropharynx;
Known contraindications to lidocaine cream;
Two or more failed attempts at LMA insertion;
Intraoperative administration of anticholinergic agents;
Any other condition present likely to influence the study outcomes.
Study Design
Study Description
Connect with a study center
Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, Guangdong 510060
ChinaActive - Recruiting
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