Phase
Condition
Allergy (Pediatric)
Allergy
Allergies & Asthma
Treatment
Colgate Dental Cream Toothpaste
CSPR Toothpaste
Clinical Study ID
Ages 18-70 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Male and female subjects, ages 18-70, inclusive.
Availability for the eight-week duration of the study.
Two sensitive teeth, which must be anterior to the molars, and demonstrate cervicalerosion/abrasion or gingival recession.
Qualifying response to tactile stimuli (Yeaple probe) as defined by a score between 10-50 gms. of force.
Qualifying response to the air blast stimuli as defined by a score of 2 or 3 on theSchiff Cold Air Sensitivity Scale.
Subjects need to satisfy the qualifying response to stimuli for both the parametersassessed (tactile or air) on two teeth to be entered into the study.
Good general health with no known allergies to products being tested.
Use of a non-desensitizing dentifrice for three months prior to entry into thestudy.
Signed Informed Consent Form.
Exclusion
Exclusion Criteria:
Gross oral pathology, chronic disease, or history of allergy to test products. 2.Advanced periodontal disease or treatment for periodontal disease (includingsurgery) within the past twelve months.
Sensitive teeth with a mobility greater than one.
Teeth with extensive/defective restorations (including prosthetic crowns), suspectedpulpitis, caries, cracked enamel, or used as abutments for removable partialdentures.
Current use of anticonvulsants, antihistamines, antidepressants, sedatives,tranquilizers, anti-inflammatory drugs, or daily use of analgesics.
Participation in a desensitizing dentifrice study or regular use of a desensitizingdentifrice within the past three months.
Current participation in any other clinical study.
Pregnant or lactating subjects.
Allergies to oral care products, personal care consumer products, or theiringredients.
Medical condition which prohibits not eating/drinking for 4 hours.
Study Design
Study Description
Connect with a study center
West China Dental Institute of Chengdu
Chengdu, Sichuan 610041
ChinaActive - Recruiting
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