A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

Key Inclusion Criteria:

1. The participant weighs greater than equal or to (≥)40 kilograms (kg) and has a bodymass index (BMI) between 16 and 38 kilograms per meter square (kg/m^2) [inclusive].

2. The participant has a documented, current diagnosis of NT2.

Key Exclusion Criteria:

1. The participant has a current medical disorder associated with excessive daytimesleepiness (EDS) other than NT2.

2. The participant has medically significant thyroid disease.

3. The participant has a history of cancer in the past 5 years. (This exclusion doesnot apply to participants with carcinoma in situ [such as basal cell carcinoma] thathas been treated and is stable, or who have been stable without further treatment.These participants may be included after approval by the medical monitor).

4. The participant has any of the following viral infections based on a positive testresult: Hepatitis B surface antigen (at screening), hepatitis C virus (HCV) antibody (at screening), human immunodeficiency virus (HIV) antibody/antigen (at screening).

5. The participant has a clinically significant history of head injury or head trauma.

6. The participant has history of epilepsy, seizure, or convulsion (exception for asingle febrile seizure in childhood).

7. The participant has a history of cerebral ischemia, transient ischemic attack (<5years from screening), intracranial aneurysm, or arteriovenous malformation.