Ropivacaine Concentration and Rebound Pain

Inclusion Criteria:

• Patients with distal radius fracture, scheduled for volar plate surgery

• Surgery up to 20 days after fracture trauma

• 18 to 80 years old (inclusive)

• ASA 1, 2 or stable ASA 3

• Body Mass Index (BMI) 18 to 40 kg/m2 (inclusive)

• Weight of 50 kg or more

• Ability to communicate sufficiently in a scandinavian language

• Capable of giving a signed informed consent

• Ability and willingness to understand og be compliant to the study

Exclusion Criteria:

• Contemporaneous painful injuries

• Existing long-term pain

• Peripheral nerve damage in the arm with radius fracture

• Patients who prior to fracture trauma use opioids, psycothropic drugs or medication,with or without prescription, with significantly sedative effect on regular basis.

• Excessive use of alcohol (more than 15 units of alchol per week for men, more than 8units of alchol per week for women, or patients reporting to be incapable ofavoiding alcohol as long as they use strong opioids).

• Progressive neurologic disease (inclusive diabetic neuropathy).

• Skin infection at the site for brachial plexus nerve block

• Other contraindications for brachial plexus nerve block

• Contraindications for ropivacaine, paracetamol, etoricoxib, dexamehtasone oroxycodone

• Previous allergic reaction to local anaesthetics or etoricoxib, dexamethasone,oxycodone or paracetamol.

• Pregnant or breast-feeding women at surgery day (they do not get excluded if theybecome pregnant in the follow up period after intervention and surgery)