Mindfulness-Based Ecological Momentary Intervention for Opioid Use Disorder and Chronic Pain

Last updated: September 29, 2025
Sponsor: Arizona State University
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Opioid Use Disorder

Chronic Pain

Pain

Treatment

Mindfulness based smartphone app

Clinical Study ID

NCT06947122
STUDY00019109
  • Ages > 18
  • All Genders

Study Summary

The goal of this clinical trial is to evaluate whether a smartphone app-based ecological momentary intervention called Mindful Journey, which teaches mindfulness skills, can support adults in recovery from both opioid use disorder and chronic pain. The primary objective of this pilot study is to assess the feasibility and acceptability of Mindful Journey in this population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18 years of age or older

  • fluent in English

  • enrollment in medication-assisted treatment for opioid use disorder

  • report at least bothersome chronic pain, as indicated by Graded Chronic PainScale-Revised

  • has a smartphone.

Exclusion

Exclusion Criteria:

  • self-reporting of chronic malignant pain (e.g., cancer) or systemic inflammatorydisease (e.g., rheumatoid arthritis, ankylosing spondylitis, lupus, and sarcoidosis)

  • self-reporting of psychotic disorder symptoms

  • participated in the previous phase of the study in which participants providedfeedback to inform the development of the Mindful Journey app.

Study Design

Total Participants: 10
Treatment Group(s): 1
Primary Treatment: Mindfulness based smartphone app
Phase:
Study Start date:
October 01, 2025
Estimated Completion Date:
December 31, 2026

Study Description

There is a paucity of interventions for co-occurring opioid use disorder and chronic pain. Difficulty with emotion regulation is a key shared vulnerability factor underlying both conditions. Mindfulness-Based Interventions (MBIs) are a promising intervention approach, as they target core skills that can improve emotion regulation. However, research on MBIs for co-morbid opioid use disorder and chronic pain is limited. Existing MBIs are also limited by not providing adequate support "in the moment" when individuals are in high-risk situations. A responsive, momentary MBI for co-occurring opioid use disorder and chronic pain may be highly promising, but has yet to be established. In the present study, we will be evaluating a smartphone app-based ecological momentary intervention, called Mindful Journey, for individuals with opioid use disorder and chronic pain. The core feature of the app is training in mindful acceptance and savoring skills via momentary "just-in-time" delivery of brief video-based exercises when individuals report elevations in challenging emotional states (e.g., craving, stress, and pain) and/or decreases in positive affect based upon ecological momentary assessments.

Connect with a study center

  • Arizona State University

    Phoenix, Arizona 85004
    United States

    Site Not Available

  • Arizona State University

    Phoenix 5308655, Arizona 5551752 85004
    United States

    Site Not Available

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