Emergency Medical Services (EMS) Telehealth to Speed STEMI Reperfusion

Last updated: April 1, 2026
Sponsor: Wake Forest University Health Sciences
Overall Status: Completed

Phase

N/A

Condition

Myocardial Ischemia

Circulation Disorders

Coronary Artery Disease

Treatment

Telehealth

Clinical Study ID

NCT06945900
IRB00094324
  • Ages > 30
  • All Genders

Study Summary

The aim of this study is to evaluate the impact of a Telehealth program on the time from First Medical Contact (FMC) to Reperfusion in STEMI (ST-elevation myocardial infarction) patients, by supporting local paramedics in their care delivery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All patients calling 9-1-1 in Wilkes County with possible STEMI as determined by theon scene paramedics will be included in the data.

Exclusion

Exclusion Criteria:

  • As this is a Quality Surveillance study, subjects will not be excluded.

Study Design

Total Participants: 11
Treatment Group(s): 1
Primary Treatment: Telehealth
Phase:
Study Start date:
June 18, 2025
Estimated Completion Date:
December 31, 2025

Study Description

STEMI (ST-elevation myocardial infarction) is the most severe type of heart attack and carries a 30-day mortality of nearly 8%. Reperfusion therapy is the mainstay of treatment for STEMI, either by percutaneous coronary intervention (PCI) or fibrinolytics. Delays in reperfusion are associated with negative health outcomes. Specifically, each 30-minute delay in reperfusion corresponds to a 7.5% decrease in 1-year survival. The current body of literature clearly shows that rural EMS agencies often have longer transport times, which makes the 90-minute first medical contact (FMC) to PCI time goal difficult to achieve. Approximately 16% of Americans live more than an hour from a PCI-capable facility, reinforcing the need for timely therapies in rural prehospital settings to decrease heart muscle damage (disability) and mortality. An analysis of a large national EMS database, which showed that FMC to PCI times were longer for patients treated by rural EMS agencies even after these times were adjusted for distance to destination hospital.8In addition, preliminary data for Cherokee Tribal EMS, serving the Eastern Band of Cherokee Indians on the Qualla Boundary and its surrounding communities, show that none of their patients who called 9-1-1 for a STEMI received reperfusion within the AHA time goal. The American College of Cardiology and AHA support prehospital fibrinolytics when timely PCI cannot be performed. STEMI telehealth programs have yet to be implemented and tested in the United States.

Connect with a study center

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina 27157
    United States

    Site Not Available

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