PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

Last updated: January 30, 2026
Sponsor: University of Utah
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Precision Exercise Regimen for Cancer Care (PERCC)

Clinical Study ID

NCT06945484
HCI162865
  • Ages > 18
  • All Genders

Study Summary

This study is designed to evaluate whether a precision exercise regimen is feasible to implement within cancer populations, specifically stage II-III primary lung cancer patients receiving multimodal therapy, and delivered through telehealth.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Ages 18 and older at time of diagnosis

  • Patient diagnosed with stage II and III non-small cell lung cancer (NSCLC)

  • Patient receives either neoadjuvant chemotherapy or immunotherapy and surgery

  • Patient able to follow direction and complete questionnaires in English or Spanish

  • Patient agrees to complete the PERCC intervention

Exclusion

Exclusion Criteria:

  • Morbidly obese (BMI >40 kg/m2 ) or anorexic (BMI <17.5 kg/m2 )

  • Abnormalities on screening physical exam per study physicians or physical therapistto contraindicate participation in exercise program compliance

  • Alcohol or drug abuse, significant mental or emotional problems that would interferewith compliance (assessed by NCCN Distress Thermometer)

  • Patient scheduled to receive single modality cancer treatment (unimodal therapy),scheduled to begin treatment within 2 weeks of the pre-treatment clinic visit, orfor whom treatment has already started

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: Precision Exercise Regimen for Cancer Care (PERCC)
Phase:
Study Start date:
November 21, 2025
Estimated Completion Date:
December 31, 2030

Study Description

This is a pilot study evaluating the feasibility of the Precision Exercise Regimen for Cancer Care (PERCC) intervention in stage II and stage III Non-Small Cell Lung Cancer (NSCLC) patients receiving multimodal therapy at the Huntsman Cancer Institute (HCI) at the University of Utah. Eligible patients will begin the intervention at the pre-treatment clinic visit and continue until approximately two months post-surgery.

The PERCC intervention is a virtually supervised home-based exercise program. Participants will engage in exercise starting at least two weeks before receiving their first neoadjuvant treatment for lung cancer and continuing until two months after receiving surgical treatment. The exercise modes will include basic transfer and calisthenics mobility, aerobic, and resistance exercises and will be performed in various postures (supine, sitting, standing, and walking) with variable challenges (level walking, bending, inclines, steps, and squatting).

Connect with a study center

  • University of Texas Medical Branch at Galveston

    Galveston, Texas 77555
    United States

    Site Not Available

  • University of Texas Medical Branch at Galveston

    Galveston 4692883, Texas 4736286 77555
    United States

    Active - Recruiting

  • Huntsman Cancer Institute

    Salt Lake City, Utah 84112
    United States

    Site Not Available

  • Huntsman Cancer Institute

    Salt Lake City 5780993, Utah 5549030 84112
    United States

    Active - Recruiting

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