A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes

Inclusion Criteria:

• Have no significant body weight change for the 3 months prior to screening

Part A and Part E:

• Are considered healthy

• Have a body mass index (BMI) of 22 to 35 kilograms per square meter (kg/m2) atscreening

Part B:

• Have a BMI of 27 to 45 kg/m2 at screening

Part C:

• Have a BMI of 25 to 45 kg/m2 at screening

Part D:

• Have type 2 diabetes

• Have hemoglobin A1C (HbA1c) ≥6.5% and ≤10.5% at screening

• Have a BMI of 27 to 45 kg/m2 at screening

Exclusion Criteria:

• Have had an acute cardiovascular condition within the past 6 months prior toscreening

• Have liver disease or pancreatitis

• Have used medications for weight loss within the 3 months prior to screening

Parts A, B, C, E:

• Have any form of diabetes

Part D:

• Have type 1 diabetes