European Real-World Registry for Use of the Ion Endoluminal System

Inclusion Criteria:

• Patient is aged 18 years or older at time of consent.

• Patient is planned to undergo a lung lesion biopsy(s) and/or localizationprocedure(s) utilizing the Ion endoluminal system.

• Patient is willing and able to give written informed consent for clinical studyparticipation.

Exclusion Criteria:

• Patient is participating in an interventional research study or research study withinvestigational agents with an unknown safety profile that would interfere withparticipation in this study or study results.

• Female patient that is pregnant or breast feeding as determined by standard sitepractices.

• Patient is legally incapacitated or in a legal/court ordered institution or is partof a known vulnerable population, including but not limited to dependency on thesponsor, hospital or study doctor.

• Patient is not willing to comply with post-procedure study participationrequirements.

• Investigator, in their professional opinion, has decided that it is in the patient'sbest interest to not participate in the clinical study.