Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis

Last updated: April 16, 2026
Sponsor: AstraZeneca
Overall Status: Active - Recruiting

Phase

N/A

Condition

Sarcopenia

Polymyositis (Inflammatory Muscle Disease)

Neuropathy

Treatment

Ravulizumab

Clinical Study ID

NCT06909253
D9281R00004
  • Ages > 18
  • All Genders

Study Summary

The Polish multicentre observational (non-interventional) study aiming to collect data on the management and clinical outcomes of patients with gMG that received ravulizumab.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult (aged ≥18 years) patients with gMG, naive to complement inhibitors, receivingravulizumab treatment in the frames of NDP in Poland.

  • Patients willing to participate in the study and signed Informed Consent Form (ICF).

  • Vaccination against N. meningitidis

Exclusion

Exclusion Criteria:

  • Those who plan to participate in gMG clinical trial on/after the date of firstravulizumab infusion through NDP.

  • Cognitive incapacity, unwillingness or language barriers precluding adequateunderstanding or cooperation.

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Ravulizumab
Phase:
Study Start date:
May 15, 2025
Estimated Completion Date:
December 31, 2029

Study Description

The Polish, prospective, multicenter, observational, cohort study designed to collect longitudinal data on the management and clinical outcomes of patients with gMG naive to complement inhibitors who received ravulizumab in the scope of routine clinical practice within the frames of National Drug Program (NDP) for up to 42 months (~ 6 months baseline and ~36 months follow-up).

Connect with a study center

  • Research Site

    Bydgoszcz,
    Poland

    Active - Recruiting

  • Research Site

    Bydgoszcz 3102014,
    Poland

    Site Not Available

  • Research Site

    Gdansk,
    Poland

    Active - Recruiting

  • Research Site

    Gdansk 3099434,
    Poland

    Site Not Available

  • Research Site

    Katowice,
    Poland

    Site Not Available

  • Research Site

    Katowice 3096472,
    Poland

    Site Not Available

  • Research Site

    Krakow,
    Poland

    Active - Recruiting

  • Research Site

    Krakow 3094802,
    Poland

    Site Not Available

  • Research Site

    Lodz,
    Poland

    Active - Recruiting

  • Research Site

    Lodz 3093133,
    Poland

    Site Not Available

  • Research Site

    Lublin,
    Poland

    Active - Recruiting

  • Research Site

    Lublin 765876,
    Poland

    Site Not Available

  • Research Site

    Poznan,
    Poland

    Site Not Available

  • Research Site

    Poznan 3088171,
    Poland

    Site Not Available

  • Research Site

    Szczecin,
    Poland

    Site Not Available

  • Research Site

    Szczecin 3083829,
    Poland

    Site Not Available

  • Research Site

    Warsaw,
    Poland

    Active - Recruiting

  • Research Site

    Warsaw 756135,
    Poland

    Site Not Available

  • Research Site

    Wroclaw,
    Poland

    Active - Recruiting

  • Research Site

    Wroclaw 3081368,
    Poland

    Site Not Available

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