Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis

Last updated: June 18, 2025
Sponsor: AstraZeneca
Overall Status: Active - Recruiting

Phase

N/A

Condition

Polymyositis (Inflammatory Muscle Disease)

Neuropathy

Sarcopenia

Treatment

Ravulizumab

Clinical Study ID

NCT06909253
D9281R00004
  • Ages > 18
  • All Genders

Study Summary

The Polish multicentre observational (non-interventional) study aiming to collect data on the management and clinical outcomes of patients with gMG that received ravulizumab.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult (aged ≥18 years) patients with gMG, naive to complement inhibitors, receivingravulizumab treatment in the frames of NDP in Poland.

  • Patients willing to participate in the study and signed Informed Consent Form (ICF).

  • Vaccination against N. meningitidis

Exclusion

Exclusion Criteria:

  • Those who plan to participate in gMG clinical trial on/after the date of firstravulizumab infusion through NDP.

  • Cognitive incapacity, unwillingness or language barriers precluding adequateunderstanding or cooperation.

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Ravulizumab
Phase:
Study Start date:
May 15, 2025
Estimated Completion Date:
December 31, 2029

Study Description

The Polish, prospective, multicenter, observational, cohort study designed to collect longitudinal data on the management and clinical outcomes of patients with gMG naive to complement inhibitors who received ravulizumab in the scope of routine clinical practice within the frames of National Drug Program (NDP) for up to 42 months (~ 6 months baseline and ~36 months follow-up).

Connect with a study center

  • Research Site

    Bydgoszcz,
    Poland

    Active - Recruiting

  • Research Site

    Gdansk,
    Poland

    Site Not Available

  • Research Site

    Katowice,
    Poland

    Site Not Available

  • Research Site

    Krakow,
    Poland

    Site Not Available

  • Research Site

    Lublin,
    Poland

    Site Not Available

  • Research Site

    Poznan,
    Poland

    Site Not Available

  • Research Site

    Szczecin,
    Poland

    Site Not Available

  • Research Site

    Warsaw,
    Poland

    Site Not Available

  • Research Site

    Wroclaw,
    Poland

    Site Not Available

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