Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

Last updated: March 18, 2025
Sponsor: Mayo Clinic
Overall Status: Active - Recruiting

Phase

N/A

Condition

Bladder Cancer

Urothelial Carcinoma

Bladder Carcinoma

Treatment

Non-Interventional Study

Clinical Study ID

NCT06891209
23-007176
23-007176
NCI-2025-00372
  • Ages > 18
  • All Genders

Study Summary

This study explores and compares health-related quality of life and urinary outcomes in postoperative partial cystectomy and matched radical cystectomy patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Currently living partial cystectomy patients in Mayo Urology's cystectomy registryand patients undergoing radical or partial cystectomy

  • Matched 2:1 living radical cystectomy to partial cystectomy patients

  • Either urothelial or non-urothelial histology

Exclusion

Exclusion Criteria:

  • Partial cystectomy patients that underwent subsequent radical cystectomy

Study Design

Total Participants: 1000
Treatment Group(s): 1
Primary Treatment: Non-Interventional Study
Phase:
Study Start date:
January 15, 2025
Estimated Completion Date:
January 31, 2027

Study Description

PRIMARY OBJECTIVES:

I. Explore and compare urinary outcomes in postoperative partial cystectomy patients and matched radical cystectomy patients through patient-filled questionnaires.

II. Explore and compare health related quality of life in postoperative partial cystectomy and matched radical cystectomy patients using patient-filled questionnaires.

III. Explore the relationship of patient-specific characteristics, ranging from demographic characteristics and clinicopathologic characteristics, on variation in HRQOL and urinary outcomes among the partial cystectomy and radical cystectomy cohorts.

OUTLINE: This is an observational study.

Patients complete questionnaires and have their medical records reviewed on study.

Connect with a study center

  • Mayo Clinic in Rochester

    Rochester, Minnesota 55905
    United States

    Active - Recruiting

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