Phase
Condition
Healthy Volunteers
Treatment
BMS-986460
Clinical Study ID
Ages 18-60 Male Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria
Participants must be healthy as determined by no clinically significant deviationfrom normal in medical history, physical examination, vital signs, 12-lead ECGs,echocardiogram or clinical laboratory assessments, as determined by theinvestigator.
Participants must have a Body mass index (BMI) between 18.0 and 35.0 kilograms/metersquare (kg/m2), inclusive.
Male participants who are sexually active with individuals of childbearing potential (IOCBP) must agree to follow instructions for methods of contraception.
Exclusion
Exclusion Criteria:
Participants with prior exposure to BMS-986460 or with a prior history of heartfailure, ischemic heart diseases, clinically significant cardiac arrythmias, or longQT syndrome are excluded.
Participants with left ventricular ejection fraction (≤ 50%) at screening areexcluded.
Participants with history of anaphylactic reactions are excluded.
Participants with current or recent (within 3 months of intervention administration)gastrointestinal disease that, in the opinion of the investigator, could affect theabsorption of study intervention are excluded.
Participants with history of Gilbert's syndrome are excluded.
Other protocol-defined Inclusion/Exclusion criteria apply.
Study Design
Connect with a study center
ICON Lenexa
Lenexa, Kansas 66219
United StatesActive - Recruiting
Local Institution - 0001
Lenexa, Kansas 66219
United StatesSite Not Available
Local Institution - 0002
Lenexa, Kansas 66219
United StatesSite Not Available
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