Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease

Last updated: July 16, 2025
Sponsor: Jiani Wu
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Acupuncture and Moxibustion (AM)

Sham Acupuncture and Moxibustion (Sham-AM)

Clinical Study ID

NCT06874803
HLCMHPP2023003
  • Ages 30-80
  • All Genders

Study Summary

This study evaluates the clinical effect and safety of acupuncture combined with moxibustion in improving motor symptoms of early-stage Parkinson's Disease (PD) patients, by assessing the changes in UPDRS scores. It also explores objective factors affecting the acupuncture effect and investigates the functional MRI mechanisms of acupuncture in PD treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Participants must meet all of the following criteria:

  1. Diagnosed with Parkinson's disease (PD) according to the 2016 Chinese 2. DiagnosticCriteria for Parkinson's Disease.

  2. Hoehn-Yahr stage <3 (mild to moderate PD). 4. Age between 30 and 80 years (inclusive). 5. Signed informed consent indicating voluntary participation.

Exclusion

Exclusion Criteria:

Participants meeting any of the following criteria will be excluded:

  1. Diagnosed with Parkinson-plus syndromes or other secondary parkinsonism.

  2. Prior history of deep brain stimulation (DBS) surgery.

  3. Severe cerebrovascular disease, brain trauma, or history of craniotomy.

  4. Severe dementia or psychiatric disorders that prevent cooperation with studyprocedures.

  5. Severe coagulation disorders.

  6. Presence of severe systemic organ dysfunction (cardiac, pulmonary, hepatic, renal,endocrine, or metabolic disorders).

  7. Pregnant or breastfeeding women.

  8. History of allergic reaction to acupuncture or moxibustion.

  9. Prior treatment with acupuncture or moxibustion within the past three months.

  10. Participation in another clinical trial within the past three months.

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: Acupuncture and Moxibustion (AM)
Phase:
Study Start date:
August 01, 2024
Estimated Completion Date:
August 31, 2026

Connect with a study center

  • Guang'anmen Hospita, China Academy of Chinese Medical Sciences

    Beijing, Beijing 100000
    China

    Active - Recruiting

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