Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only

Last updated: April 2, 2026
Sponsor: Resilience
Overall Status: Active - Recruiting

Phase

3

Condition

Cancer

Neoplasms

Treatment

Resilience PRO

Clinical Study ID

NCT06867705
RC-102
2024-A01584-43 (ID RCB)
N° Eudamed: CIV-25-01-050834
  • Ages > 18
  • All Genders

Study Summary

The goal of this clinical trial is to learn if Resilience PRO, a digital solution performing remote symptoms monitoring, can improve the quality of life of patients with a diagnosis of cancer receiving systemic anticancer treatment.

The main question it aims to answer is:

  • Do patients with a diagnosis of cancer receiving systemic anticancer therapy and using Resilience PRO have an improved quality of life? Researchers will compare patients using Resilience PRO plus care as usual to patients receiving care as usual only.

Participants in the intervention arm will use Resilience PRO, a mobile phone application regularly asking participants about their symptoms. For clinically important symptoms, an alert is sent to the care team that can incorporate that information to timely adjust the care of the participants. Participants both in the control arm and in the intervention arm will further receive care as usual.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age: Adults ≥ 18 years.

  • Informed Consent: Patient giving signed informed consent to participate in the RC - 102 clinical study.

  • Diagnosis: Patients with cancer at any stage.

  • Systemic Treatment

  • Remote Monitoring Eligibility: Access to a smartphone

  • Language: Ability to understand and communicate in the language(s) in which thetrial is conducted.

Exclusion

Exclusion Criteria:

  • Age: Patients under 18 years of age.

  • Life Expectancy: Patients with a life expectancy of less than 6 months as estimatedby the treating physician.

  • Concurrent remote monitoring

  • HSCT or CAR-T Therapy

  • Cognitive Impairment

  • Pregnancy or breastfeeding

  • Subject under administrative or judicial control

Study Design

Total Participants: 1458
Treatment Group(s): 1
Primary Treatment: Resilience PRO
Phase: 3
Study Start date:
April 01, 2025
Estimated Completion Date:
December 31, 2029

Study Description

Resilience PRO is a digital medical device (dMD CE marked, class IIa) that enables the remote monitoring of patients diagnosed with cancer receiving anticancer systemic therapy. Resilience PRO has been positively evaluated by the French health authorities (HAS, Haute Autorité de Santé) and is registered on the French LATM list (Liste des Activités de Télésurveillance Médicale).

Resilience PRO is a software medical device prescribed by cancer treating physicians to collect electronic patient-reported outcomes (ePRO). The Resilience PRO workflow comprises the following steps:

  • Step 1. Collection of ePRO

  • Step 2. Intelligent analysis and alerts

  • Step 3. Adapted care

Connect with a study center

  • Centre Hospitalier du Pays d'Aix - Centre Hospitalier Intercommunal Aix-Pertuis

    Aix-en-Provence, 13100
    France

    Active - Recruiting

  • Hôpital Privé de Provence

    Aix-en-Provence, 13080
    France

    Active - Recruiting

  • Centre Hospitalier Henri Mondor-Aurillac

    Aurillac, 15000
    France

    Active - Recruiting

  • Centre Hospitalier de la Côte Basque

    Bayonne, 64100
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Caen Normandie

    Caen, 14033
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Clermont-Ferrand

    Clermont-Ferrand, 63003
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire Grenoble - Alpes

    La Tronche, 38700
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Lille

    Lille, 59037
    France

    Active - Recruiting

  • GHICL Hôpital Saint Vincent de Paul

    Lille, 59000
    France

    Active - Recruiting

  • Hôpital Privé Jean Mermoz - Institut de Cancérologie

    Lyon, 69008
    France

    Active - Recruiting

  • AP-HM Assistance Publique - Hôpitaux de Marseille Hôpital de la Timone

    Marseille, 13005
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Nantes

    Nantes, 44093
    France

    Active - Recruiting

  • Hôpital Privé du Confluent

    Nantes, 44200
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Nice

    Nice, 06000
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire de Nîmes

    Nîmes, 30029
    France

    Active - Recruiting

  • AP-HP Hôpitaux Universitaires La Pitié Salpêtrière

    Paris, 75013
    France

    Active - Recruiting

  • Clinique Mutualiste Bretagne Occidentale

    Quimper, 29000
    France

    Active - Recruiting

  • Hôpital Privé de la Loire (HPL) - Saint Etienne

    Saint-Etienne, 42100
    France

    Active - Recruiting

  • Clinique Mutualiste de l'Estuaire

    Saint-Nazaire, 44606
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire Sud Réunion

    Saint-Pierre, 97448
    France

    Active - Recruiting

  • Hôpital Privé de la Loire (HPL) - Saint Etienne

    Saint-Étienne, 42100
    France

    Site Not Available

  • Centre Clinical Elsan

    Soyaux, 16800
    France

    Active - Recruiting

  • Centre Hospitalier Intercommunal Toulon - La Seyne sur Mer

    Toulon, 83056
    France

    Active - Recruiting

  • Clinique Pasteur

    Toulouse, 31076
    France

    Active - Recruiting

  • Centre de Cancérologie Les Dentellières

    Valenciennes, 59300
    France

    Active - Recruiting

  • Clinique Teissier

    Valenciennes, 59300
    France

    Active - Recruiting

  • Gustave Roussy

    Villejuif, 94805
    France

    Active - Recruiting

  • University Hospital Augsburg - UKA

    Augsburg, 86156
    Germany

    Active - Recruiting

  • Helios Klinikum Bad Saarow

    Bad Saarow, 15526
    Germany

    Active - Recruiting

  • Katholisches Klinikum Bochum UK St. Josef - Hospital

    Bochum, 44791
    Germany

    Active - Recruiting

  • UK Hamburg- Eppendorf (UKE)

    Hamburg, 20246
    Germany

    Active - Recruiting

  • Medizinische Hochschule Hannover

    Hanover, 30625
    Germany

    Active - Recruiting

  • MVZ Aschaffenburg-Alzenau

    Hösbach, 63768
    Germany

    Active - Recruiting

  • Universitätsklinikum Schleswig-Holstein (UKSH), Campus Kiel

    Kiel, 24105
    Germany

    Active - Recruiting

  • Universitätsklinikum Schleswig-Holstein (UKSH), Campus Lübeck

    Lübeck, 23538
    Germany

    Active - Recruiting

  • Onkomedeor MVZ Perlach

    München, 81737
    Germany

    Active - Recruiting

  • Universitätsklinikum Tuebingen

    Tübingen, 72076
    Germany

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.