Vitamin K and Cognition in Coronary Heart Disease (NutriCog)

Inclusion Criteria:

• Men and women

• Age 60 years and older

• Medically documented stable Coronary Heart Disease (CHD)

• Daily dietary intakes of phylloquinone <150 mcg

• Non-consumption of vitamin K supplements (i.e. K1 or K2, singly or in combinationwith other nutrients), or other cognitive aids

• Good French or English understanding

• Physical exercise not exceeding 2.5 hours/week of moderate to vigorous aerobicactivity

• Capacity and willingness to sign informed consent

Exclusion Criteria:

• Recent acute coronary syndrome (<3 months) or recent coronary revascularization (bypass surgery or percutaneous coronary intervention, <3 months)

• Known left ventricular dysfunction (LVEF < 40%) or chronic heart failure

• Recent modification of medication (<2 weeks)

• Warfarin (Coumadin) use

• Cognitive impairment (based on telephone version of the Mini-Mental StateExamination test, score <19/23)

• Diagnosis of depression or uncontrolled anxiety

• Malabsorption disorder (advanced liver disease, Crohn's disease)

• Patient with auditory or vision impairments not properly corrected by glasses orhearing aids

• Unable to read the informed consent form or unable to understand the oralexplanations provided by the assessor