Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

Last updated: May 27, 2026
Sponsor: Dogwood Therapeutics Inc.
Overall Status: Active - Recruiting

Phase

2

Condition

Neoplasms

Chronic Pain

Pain

Treatment

Halneuron (Open Label Extension)

Halneuron

Placebo

Clinical Study ID

NCT06848348
HAL-CINP-203
  • Ages > 18
  • All Genders

Study Summary

A randomized study to determine safety and efficacy of a series of subcutaneous (SC) injections of HAL in patients with CINP, compared to matching placebo injections. After that, subjects may have the option to enter an Open Label extension phase, where available, in which all subjects will receive Halneuron.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male or female patients aged ≥18 years.

  • Neuropathic pain has been present and is attributed to platinum and/or taxanechemotherapy.

  • Patient has received a cancer chemotherapy regimen that included taxanes and/orplatinum and has no active or discernible disease progression.

Exclusion

Exclusion Criteria:

  • Current neuropathic pain with symptoms similar to CINP but attributed to causesother than platinum or taxane chemotherapy.

  • Patients who have received HAL at any time prior to screening.

Study Design

Total Participants: 240
Treatment Group(s): 3
Primary Treatment: Halneuron (Open Label Extension)
Phase: 2
Study Start date:
February 21, 2025
Estimated Completion Date:
August 31, 2026

Connect with a study center

  • Central Recruiting Site

    Sheffield, Alabama 35660
    United States

    Active - Recruiting

  • Central Recruiting Site

    Glendale, Arizona 85308
    United States

    Active - Recruiting

  • Central Recruiting Site

    Phoenix, Arizona 85022
    United States

    Active - Recruiting

  • Central Recruiting Site

    Fair Oaks, California 95628
    United States

    Active - Recruiting

  • Central Recruiting Site

    Fountain Valley, California 92708
    United States

    Active - Recruiting

  • Central Recruiting Site

    Los Angeles, California 91307
    United States

    Active - Recruiting

  • Central Recruiting Site

    Santa Rosa, California 95403
    United States

    Active - Recruiting

  • Central Recruiting Site

    Wheat Ridge, Colorado 80033
    United States

    Active - Recruiting

  • Central Recruiting Site

    Jacksonville, Florida 32205
    United States

    Active - Recruiting

  • Central Recruiting Site

    Lakeland, Florida 33812
    United States

    Active - Recruiting

  • Central Recruiting Site

    Orlando, Florida 32832
    United States

    Active - Recruiting

  • Central Recruiting Site

    Port Charlotte, Florida 33952
    United States

    Active - Recruiting

  • Central Recruiting Site

    Tampa, Florida 33613
    United States

    Active - Recruiting

  • Central Recruiting Site

    Jacksonville 4160021, Florida 4155751 32205
    United States

    Active - Recruiting

  • Central Recruiting Site

    Gurnee, Illinois 60031
    United States

    Active - Recruiting

  • Central Recruiting Site

    Lake Charles, Louisiana 70605
    United States

    Active - Recruiting

  • Central Recruiting Site

    Fenton, Missouri 63026
    United States

    Active - Recruiting

  • Central Recruiting Site

    Las Vegas, Nevada 89109
    United States

    Active - Recruiting

  • Central Recruiting Site

    Garden City, New York 11530
    United States

    Active - Recruiting

  • Central Recruiting Site

    Williamsville, New York 14221
    United States

    Active - Recruiting

  • Central Recruiting Site

    Winston-Salem, North Carolina 27103
    United States

    Active - Recruiting

  • Central Recruiting Site

    Houston, Texas 77346
    United States

    Active - Recruiting

  • Central Recruiting Site

    McAllen, Texas 78504
    United States

    Active - Recruiting

  • Central Recruiting Site

    Salt Lake City, Utah 84107
    United States

    Active - Recruiting

  • Central Recruiting Site

    Madison, Wisconsin 53715
    United States

    Active - Recruiting

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