Preventing Type 2 Diabetes in Black Emergent Adult

Last updated: July 28, 2025
Sponsor: University of North Carolina, Chapel Hill
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hypertriglyceridemia

Diabetes Mellitus, Type 2

Obesity

Treatment

Appetite Awareness Training (AAT) and Diabetes Prevention Program (DPP)

Diabetes Prevention Program (DPP)

Appetite Awareness Training (AAT)

Clinical Study ID

NCT06848244
25-0125
  • Ages 18-25
  • Female
  • Accepts Healthy Volunteers

Study Summary

Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults. Though numerous factors affect these disparities, one modifiable risk factor may be that of binge eating (BE), which increases risk for binge-eating disorder (BED), which is associated with severe obesity, and often precedes a T2DM diagnosis, beginning in childhood or adolescence. Nearly 30% of Black women with obesity report binge eating episodes. Furthermore, given that binge and overeating may disparately increase the odds of obesity in Black adults (15-fold increase vs. 6-fold increase in White adults), reducing this behavior will be critical to prevent continued disparities in T2DM diagnosis. Given that Black women have the highest rates of obesity in the nation (57%), report disparate rates of weight gain between young adulthood and mid adulthood, and report disparate rates of emotional eating in adolescence, which is a risk factor for BE, one pathway to reducing disparities in T2DM risk in Black women may be to reduce binge eating and prevent weight gain in emerging adulthood (ages 18-25).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Black women

  • between 18-25 years of age

  • BMI ≥ 25 kg/m^2

  • At least one binge eating episode weekly

  • Prediabetic

  • Have access to a smartphone

Exclusion

Exclusion Criteria:

  • Have no internet access

  • Currently type 2 diabetic

  • Currently pregnant

  • Are in substance use treatment

  • Have received prior or planned bariatric surgery

Study Design

Total Participants: 100
Treatment Group(s): 3
Primary Treatment: Appetite Awareness Training (AAT) and Diabetes Prevention Program (DPP)
Phase:
Study Start date:
June 30, 2025
Estimated Completion Date:
December 31, 2030

Study Description

Aim 1. Use formative research to gather recommendations to Tailor AAT+DPP to Black Emergent Adult (EA) Women (Year 1).

Aim 2. Utilize community-engaged and user-centered design methods to adapt a mobile intervention to prevent T2DM in Black women at risk for BED (Year 2).

Aim 3. Conduct a pilot randomized trial to examine the feasibility and acceptability, and preliminary efficacy of the adapted AAT+ DPP intervention (Years 3-4; Analysis Year 5).

Connect with a study center

  • UNC-Chapel Hill

    Chapel Hill, North Carolina 27599
    United States

    Active - Recruiting

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