Exploring the Potential Benefits of Probiotic Yogurt

Inclusion Criteria:

1. Meet the Rome IV diagnosis criteria for chronic constipation;

2. Patients who are able to understand clinical studies and are committed to complyingwith study requirements and procedures;

3. Age 18-65. -

Exclusion Criteria:

1. Systemic (diabetes, autoimmune diseases, cancer), gastrointestinal or liver diseasesknown to be associated with alterations in the gut microbiota;

2. Patients who are pregnant or lactating;

3. have taken antimicrobials, probiotics, or drugs that inhibit stomach acid orgastrointestinal motility in the past 6 weeks;

4. Patients who changed their diet type during the study;

5. Patients who are allergic or intolerant to any component of the investigationalproduct formulation;

6. Patients with cardiovascular, cerebrovascular, liver, kidney and hematopoieticsystem and other serious diseases and endocrine diseases, mental patients;

7. Stop taking the tested sample or add other drugs in the middle, unable to judge theefficacy or incomplete data;

8. short-term use of objects related to the function of the test, affecting thejudgment of the result;

9. have been dieting, exercising excessively, taking weight loss medications or takingmedications that may affect appetite in the past 3 months;

10. Current or past excessive use of alcohol, drugs, or supplements that may causeintestinal dysfunction or interfere with the evaluation of the efficacy of the studyproduct -