Connect-Home: Alzheimer's Disease and Related Dementias

Last updated: May 12, 2025
Sponsor: University of North Carolina, Chapel Hill
Overall Status: Active - Recruiting

Phase

N/A

Condition

Dementia

Treatment

Connect-Home ADRD

Clinical Study ID

NCT06840587
24-2766
2R01NR017636-05A1
  • Ages > 19
  • All Genders

Study Summary

This study is a parallel arm, cluster randomized trial (CRT) to test the efficacy of Connect-Home ADRD, a transitional care intervention focusing on Skilled Nursing Facility (SNF) patients with Alzheimer's disease and dementias and their caregivers during transitions from SNFs to home, assisted, living, and long-term care. The primary hypothesis is that the intervention will reduce caregiver strain (Aim 1) and patient neuropsychiatric symptoms (Aim 2).

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients:

  • Ability to speak English

  • Goal of discharge to home, assisted living, or long-term care

  • Diagnosis of dementia

  • Having a caregiver willing to participate

Caregivers:

  • Ability to speak English

  • Legally authorized representative (LAR) who also provides support for the personwith ADRD

Inclusion criteria for SNFs:

  • Location within 120 miles of UNC-Chapel Hill

  • Admission of at least 75 SNF patients per year

Exclusion

Exclusion Criteria:

Patients:

  • Planned hospital readmission for procedures or treatments within 30 days postenrollment.

Caregivers:

  • LAR is a court-appointed guardian.

Study Design

Total Participants: 360
Treatment Group(s): 1
Primary Treatment: Connect-Home ADRD
Phase:
Study Start date:
April 04, 2025
Estimated Completion Date:
June 30, 2027

Study Description

Connect-Home ADRD is a Donabedian-guided intervention that introduces new structure and processes to support Skilled Nursing Facility (SNF) staff delivery of transitional care for transitions to home, assisted living, or long-term care, and post-discharge transitional care by the Dementia Caregiving Specialist (DCS).

The research objective is to test the efficacy of Connect-Home ADRD, a transitional care intervention, targeting Skilled Nursing Facility (SNF) patients with Alzheimer's disease and related dementias (ADRD) and their primary caregivers who discharge home and other settings of care. The study will be set in 12 North Carolina SNFs and in the patient's discharge destination (during intervention periods only). Using a cluster-randomized trial design, twelve SNFs will be randomly allocated to an intervention group (N=6 SNFs) and to a control group (N=6 SNFs) by a study statistician masked to SNF identity. 360 dyads of SNF patients with ADRD and caregivers will be enrolled in 12 SNFs.

Connect with a study center

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina 27599
    United States

    Active - Recruiting

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