Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

Last updated: February 19, 2025
Sponsor: University of Portsmouth
Overall Status: Active - Recruiting

Phase

N/A

Condition

Osteoarthritis

Knee Injuries

Treatment

No intervention

Clinical Study ID

NCT06829433
SHFEC 2024-007
  • Ages 40-85
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reportedability to walk without an aid for 10 minutes and to ascend and descend stairs, noneurological conditions or other musculoskeletal pathology/injury which would impactwalking gait.

Exclusion

Exclusion Criteria:

  • Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking,lacking ability to consent.

Study Design

Total Participants: 36
Treatment Group(s): 1
Primary Treatment: No intervention
Phase:
Study Start date:
May 07, 2024
Estimated Completion Date:
September 30, 2026

Study Description

People living with OA tend to be less physically active than those without the disease, which is often due to pain, stiffness and joint instability. This reduction in physical activity can lead to additional health problems down the line. When the disease becomes severe, joint replacement surgeries are sometimes performed to relieve pain and improve individuals' quality of life. However, despite reducing pain, there is little evidence to show that joint replacement surgeries encourage individuals to return to healthy physical activity levels.

Reasons for the lack of change may include a failure to address unhealthy walking and movement patterns which could still be causing pain and instability and reduced physical fitness levels.

By investigating these reasons, we hope that findings from this study will help to inform future interventions that improve clinical outcomes and quality of life for individuals with OA and post-joint replacement.

Connect with a study center

  • School of Psychology, Health and Sport Sciences, University of Portsmouth

    Portsmouth, Hampshire PO1 2ER
    United Kingdom

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.