The Characteristics of Blood Glucose Profile and the Changes of Hormones in PPDM-C Population

Last updated: February 10, 2025
Sponsor: Shanghai Changzheng Hospital
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Pancreatitis

Diabetic Macular Edema

Diabetic Neuropathy

Treatment

N/A

Clinical Study ID

NCT06826729
2024SL140
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study was to explore the characteristics of blood glucose spectrum, changes of endocrine/exocrine pancreatic function and the correlation between them in patients with PPDM-C.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male or female Chinese subjects;

  • Was ≥ 18 years old when signing the informed consent;

  • Patients with complete diagnosis of chronic pancreatitis; ④ Those whovoluntarily signed informed consent; ⑤ Those who complete serum samples inmultiple centers and put them into storage.

Exclusion

Exclusion Criteria:

  • Patients with impaired glucose tolerance but undiagnosed diabetes;

  • Patients with T1DM related autoimmune markers or other types of DM;

  • Patients with autoimmune pancreatitis, recurrent acute pancreatitis oracute onset of chronic pancreatitis;

  • Patients who underwent pancreatic surgery or related invasiveprocedures during treatment;

  • Previous or current malignant tumor; ⑥ Pregnancy or lactation; ⑦Suffering from severe heart, liver or kidney dysfunction ormalignant disease; ⑧ Failure to sign informed consent forcognitive impairment or other reasons.

Study Design

Total Participants: 2000
Study Start date:
February 11, 2025
Estimated Completion Date:
July 01, 2027

Study Description

The benefits of this study to participants include:

  1. It will help to make early diagnosis or risk screening for the potential related risks and concomitant diseases of the disease;

  2. Provide necessary suggestions for the treatment and intervention of the disease, or provide useful information for the related research of the disease.

  3. We will provide Abbott version h dynamic glucose meter and assessment of internal and external secretion function. The researcher will provide professional endocrine related lifestyle and drug guidance for the subjects according to their CGMS data.

The risks that this study may bring to participants are:

There may be some very small risks in specimen collection, including transient pain, local cyanosis, etc. a few people will have mild dizziness or extremely rare needle infection.