Phase
Condition
N/ATreatment
Control
Diet intervention
Clinical Study ID
Ages 21-50 Female Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Subjects must meet all of the inclusion criteria for participation:
Females aged 21-50 years
Chinese ethnicity
Singapore citizens, permanent residents, or long-term pass holders
Is able to complete questionnaires in English
BMI ≥ 23.0 kg/m2 but < 37.5 kg/m2
Not planning to conceive in the next 12 months from enrolment (you will be asked towithdraw once you conceive during the study period)
Not planning to leave Singapore for more than 2 consecutive calendar weeks (10working days) in the next six months from enrolment
Not currently pregnant or breastfeeding
Not currently smoking
Without history of major chronic diseases (e.g., cancer, diabetes, cardiovasculardiseases, chronic kidney disease), major infectious diseases (e.g. hepatitis B,HIV), severe gastrointestinal disorders (e.g. colitis or inflammation of the bowel,celiac disease, chronic gastritis) and major medical procedures/surgeries related tothese conditions
Without major mental health condition
Without known food allergies, especially to nuts and seafood.
Not on any special diets or having dietary restrictions (e.g. vegetarians, vegans,ketogenic, Kosher diet)
Not currently and will not be enrolled in another interventional study or studiesthat may affect weight, cardiometabolic health, gut, or brain health in the next sixmonths from enrolment
Exclusion
Exclusion Criteria:
Subjects not meeting any of the above inclusion criteria will be excluded from participation.
Additional Exclusion Criteria for MRI procedure only:
i. Shoulder width ≥60cm ii. Has any medical implants or foreign bodies, particularly related to heart, brain, or eye implants, including but not limited to pacemakers, artificial heart valves, implantable cardioverter defibrillators, ventricular assist devices, brain stimulation devices, intrauterine devices, and breast biopsies (if any implant or tissue marker has been placed) iii. History of head injury or trauma with loss of consciousness iv. Metallic dental braces or dental implants v. Having claustrophobia vi. Drinks more than 30 units of alcohol per week (1 unit = 25mL 40% spirit, 1 can of beer = 2 units, 1 standard glass of wine = 2 units)
Study Design
Study Description
Connect with a study center
Global Centre for Asian Women's Health
Singapore, 117549
SingaporeActive - Recruiting

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