Manual Acupuncture (MA) for Asymptomatic Hyperuricemia (HUA)

Last updated: March 28, 2025
Sponsor: Shenghao Tu
Overall Status: Active - Recruiting

Phase

N/A

Condition

Gout (Hyperuricemia)

Treatment

Sham acupuncture

Manual acupuncture

Clinical Study ID

NCT06824376
2023HUATJ01-V1.1(20240206)
ZY2021Z002
  • Ages > 18
  • All Genders

Study Summary

Assess the effectiveness of manual acupuncture in modulating serum uric acid levels among patients diagnosed with asymptomatic hyperuricemia.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • With serum uric acid (SUA) level >7 mg/dL after 1 month of a low-purine diet.

  • No history of gouty arthritis.

  • Has not received uric acid-lowering drug treatment or stopped uric acid- loweringdrug treatment ≥ 12 weeks.

  • 18.5kg/m2 ≤ body mass index (BMI) ≤ 30.0 kg/m2.

  • Can write informed consent.

Exclusion

Exclusion Criteria:

  • Patients with poorly controlled hypertension: systolic blood pressure (SBP) ≥ 160mmHg, diastolic blood pressure (DBP) ≥ 100 mmHg.

  • Patients with poorly controlled diabetes (hemoglobin A1c ≥ 8.4%).

  • Patients with severe liver and kidney damage: chronic kidney disease (CKD) ≥ stage 2or a serum creatinine, urea, alanine, or aspartate aminotransferase level more thantwice of the upper limit.

  • Patients with blood system diseases, such as acute and chronic leukemia,polycythemia, multiple myeloma, hemolytic anemia, lymphoma, or undergoingchemotherapy for multiple solid tumors.

  • Patients with stroke, coronary heart disease, or severe neuropsychological diseases.

  • Patients who are pregnant.

  • Illiterate or unwilling to accept acupuncture treatment.

Study Design

Total Participants: 260
Treatment Group(s): 2
Primary Treatment: Sham acupuncture
Phase:
Study Start date:
March 25, 2025
Estimated Completion Date:
December 31, 2026

Study Description

This is a multicenter randomized, single-blind, sham-controlled trial. A total of 260 eligible patients with asymptomatic hyperuricemia will be randomly assigned in a 1:1 ratio to manual acupuncture group or sham acupuncture group.

Connect with a study center

  • Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei 430030
    China

    Active - Recruiting

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