Phase
Condition
N/ATreatment
Combination Nicotine Replacement Therapy (patch and lozenge)
Clinical Study ID
Ages 18-99 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Common to all 3 RCTs:
Inclusion criteria:
age18+ years
stable mailing address (for mailing study packets if assigned to Remote Intakeand/or Remote Treatment/Assessment) within accessible range (1.5 hours) of eachstudy site (per self report)
able to read, speak & verbally comprehend English
own an iOS or Android smartphone
have a valid e-mail address that is checked regularly or have regular access to textmessages (to access follow-up assessments)
Specific to RCT 1:
Inclusion criteria:
a) daily cigarette smoker of 5+ cigarettes/day for 6+ months b) moderate or greater motivation to quit smoking (6+ on the Motivation to Stop Smoking Scale) d) agree to refrain from use of other tobacco products and use of non-study cessation treatments while participating in the trial e) Willing to be randomized to attend remote/in-person visits
Exclusion
Exclusion Criteria:
- Specific to RCT 1: a) use of tobacco/nicotine products other than cigarettes (except blunts, spliffs,cigars, little cigars, cigarillos) for average of 5_ days per week over the past 3months b) prior allergy/intolerance to NRT patch or lozenge c). pregnant,breastfeeding, or planning to become pregnant in next 4 months d) use ofvarenicline, NRT (e.g., patch, gum, lozenge), or bupropion in past 7 days forpurpose of quitting smoking e) consumption of >28 alcohol-containing drinks per weekg) high risk involvement with illicit or nonmedical prescription drugs (NIDA-modified ASSIST=27+) h) suicide attempt with at least some wish to die in past 3 months i) mental illness (such as schizophrenia, bipolar disorder, or majordepression) that led to hospitalization in the past 30 days j) unable/unwilling toprovide informed consent or follow directions, inappropriately responsive, based onstaff observations k) for participants age 21+: refusal to provide/show a pack ofcigarettes for documentation at the intake visit
Study Design
Connect with a study center
University at Buffalo
Buffalo, New York 14260
United StatesSite Not Available
University at Buffalo
Buffalo 5110629, New York 5128638 14260
United StatesActive - Recruiting
University of Pennsylvania
Philadelphia, Pennsylvania 19104
United StatesSite Not Available
University of Pennsylvania
Philadelphia 4560349, Pennsylvania 6254927 19104
United StatesActive - Recruiting

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