Effects Multimodal Mind and Body Approach for MCI

Last updated: February 3, 2025
Sponsor: Massachusetts General Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Dementia

Mild Cognitive Impairment

Memory Loss

Treatment

Experimental: A computer-based multimodal mind and body approach (cbMMBA)

A standard cognitive training group

Clinical Study ID

NCT06814483
2022p003426
  • Ages > 50
  • All Genders

Study Summary

The aim of this application is to develop a computer-based multimodal mind and body approach (CMMBA) for mild cognitive impairment (MCI). This product will provide a new, cost-effective and easily accessible treatment option for MCI and potentially other age-related dementia.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. report of cognitive decline / complaint by the patient, the patient's informant, orthe physician;

  2. cognitive impairment is confirmed by objective cognitive measures (MontrealCognitive Assessment (MoCA) and neuropsychological testing), where objectivecognitive impairment is defined as poor performance in one or more cognitivemeasures suggesting deficit in one or more cognitive domains;

  3. patient has preserved independence in functional abilities (measured by informantreport, completion of Activities of Daily Living (ADL) and Instrumental Activitiesof Daily Living (IADL) checklists);

  4. not demented;

Exclusion

Exclusion Criteria:

  1. has severe visual or hearing impairment;

  2. has pre-existing musculoskeletal or other conditions, which prohibit BDJ performanceand / or the application of acupressure at the selected points;

  3. has suffered from a neurological disorder (e.g., severe head trauma), psychiatricdisease (e.g., major depression), or any other major medical disease that couldpotentially compromise their cognition;

  4. has had prior experience with BDJ or acupressure or relaxation techniques in thepast year.

Study Design

Total Participants: 30
Treatment Group(s): 2
Primary Treatment: Experimental: A computer-based multimodal mind and body approach (cbMMBA)
Phase:
Study Start date:
December 12, 2023
Estimated Completion Date:
May 31, 2025

Study Description

The goal of this Phase I R41 (STTR) application is to develop a computer-based multimodal mind and body approach (cbMMBA) to improve the cognitive function for mild cognitive impairment (MCI). This application, if successful, will provide a cost-effective and easily accessible treatment option for MCI and other age-related dementia, significantly improve the prevention of MCI development, and directly benefit patients suffering from the highly prevalent disorder, particularly for those who may have limited access to in-person mind and body interventions.

Connect with a study center

  • Massachusetts General Hospital

    Charlestown, Massachusetts 02129
    United States

    Active - Recruiting

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