SPG Pulsed Radiofrequency for Chronic Cluster Headache

Inclusion Criteria:

• Chronic cluster headache;

• At least four attacks per week;

• Minimum age of 18 years;

• Non-response to verapamil and lithium treatment in the past, intolerance, orcontraindication to verapamil and lithium, along with non-response, intolerance, orcontraindica-tion to topiramate, or gabapentin.

Exclusion Criteria:

• Pregnancy or breastfeeding;

• Presence of cardiac pacemaker or other neuromodulatory devices;

• Pyschiatric and cognitive disorders;

• Serious drug habituation or overuse of acute-headache medication;

• History of stroke or intracranial aneurysm, or at risk for serious or acutecardiovascular events;

• Infection at the puncture site;

• Previous history of invasive treatments such as sphenopalatine ganglionradiofrequency thermocoagulation and chemical destruction.