Types of Photoplethysmographic Waves in Adult Patients with Septic Shock

Last updated: January 15, 2025
Sponsor: Hospital General de México Dr. Eduardo Liceaga
Overall Status: Active - Recruiting

Phase

N/A

Condition

Low Blood Pressure (Hypotension)

Treatment

N/A

Clinical Study ID

NCT06786364
DI/24/401/03/33
  • Ages > 18
  • All Genders

Study Summary

The objective of this study is to identify the types of Photoplethysmographic waves present in adults with septic shock and determine whether these waves correlate with other variables of tissue hypoperfusion such as capillary refil, serum lactate and mottling score.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult patients of 18 years of age and above dignossed with septic shock according tothe definition stated in Sepsis 3.0

  • Patients with axillary temperature above 36°C

  • Patients and/or family that agree to participate in such study and sign the informedconsentment

  • Patients that tolerate supine position

Exclusion

Exclusion Criteria:

  • Patients with Cardiogenic shock, hipovolemic, obstructive and distributive (neurogenic, anafilactic) shock the exception being septic shock

  • Patients with history of any type of cardiac arrhythmia

  • Patients with history of chronic hepatic disease

  • Patients with limited or diffuse systemic sclerosis

  • Patients that have scarring, nail polish or thickened nails that may impede theproper placement and accurate measurement of photoplethysmography with the pulseoximeter

  • Patients with history of heart insufficiency P- atients with septic shock thatalready have vasopressor aggents

Study Design

Total Participants: 116
Study Start date:
November 01, 2024
Estimated Completion Date:
May 30, 2025

Study Description

Photoplethysmography is the technology used in pulse oximeters in order to calculate arterial oxygen saturation and pulse rate, this technology generates a wave whose morphology has been related to blood flow and arterial tone. Recently Tusman and collaborators described a morphological classification of the photoplethysmografic wave that has a high correlation with arterial tone, such classification is divided in 6 types; Types I and II indicate vasoconstriction, Type III normal arterial tone and Types IV, V and VI describe mild, medium and severe vasodilation respectively, therefore it could be used to identify the arterial tone in those patients with septic shock. This study will identify the type of photoplethysmographic waves that are present in adults with septic shock based in the Tusman and collaborators classification, it will also describe the frequency of appearance and their correlation with other hemodynamic variables such as capillary refill, serum lactate, mottling score, heart rate, mean arterial pressure, pulse pressure and perfusion index.

Connect with a study center

  • Hospital General de México Dr. Eduardo Liceaga

    Mexico city, Cuauhtemoc 06726
    Mexico

    Active - Recruiting

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