Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Last updated: May 22, 2025
Sponsor: Lars Wiuff Andersen
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Anterior-posterior pad positioning

Double-sequential defibrillation

Anterior-lateral pad positioning

Clinical Study ID

NCT06781892
00006
  • Ages > 18
  • All Genders

Study Summary

The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Out-of-hospital cardiac arrest

  2. Age ≥ 18 years

  3. ≥ 1 manual defibrillation attempt by emergency medical services

  4. Shockable rhythm as the last known rhythm

  5. Two manual defibrillators present on-site

Exclusion

Exclusion Criteria:

  1. Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of thecardiac arrest

  2. Prior enrollment in the trial

  3. Posterior pad placement not deemed possible by on-site clinician

Study Design

Total Participants: 909
Treatment Group(s): 3
Primary Treatment: Anterior-posterior pad positioning
Phase:
Study Start date:
March 15, 2025
Estimated Completion Date:
March 01, 2029

Connect with a study center

  • Emergency Medical Services, the North Denmark Region

    Aalborg, 9000
    Denmark

    Active - Recruiting

  • Danish Air Ambulance, Danish Regions

    Aarhus N, 8200
    Denmark

    Site Not Available

  • Prehospital Emergency Medical Services, Central Denmark Region

    Aarhus N, 8200
    Denmark

    Active - Recruiting

  • Copenhagen Emergency Medical Services, the Capital Region of Denmark

    Ballerup, 2750
    Denmark

    Site Not Available

  • The Prehospital Center, Region Zealand

    Næstved, 4700
    Denmark

    Site Not Available

  • Emergency Medical Services, the Region of Southern Denmark

    Vejle, 7100
    Denmark

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.