Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Last updated: March 18, 2025
Sponsor: Lars Wiuff Andersen
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Double-sequential defibrillation

Anterior-posterior pad positioning

Anterior-lateral pad positioning

Clinical Study ID

NCT06781892
00006
  • Ages > 18
  • All Genders

Study Summary

The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Out-of-hospital cardiac arrest

  2. Age ≥ 18 years

  3. ≥ 1 manual defibrillation attempt by emergency medical services

  4. Shockable rhythm as the last known rhythm

  5. Two manual defibrillators present on-site

Exclusion

Exclusion Criteria:

  1. Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of thecardiac arrest

  2. Prior enrollment in the trial

  3. Posterior pad placement not deemed possible by on-site clinician

Study Design

Total Participants: 909
Treatment Group(s): 3
Primary Treatment: Double-sequential defibrillation
Phase:
Study Start date:
March 15, 2025
Estimated Completion Date:
March 01, 2029

Connect with a study center

  • Emergency Medical Services, the North Denmark Region

    Aalborg, 9000
    Denmark

    Site Not Available

  • Danish Air Ambulance, Danish Regions

    Aarhus N, 8200
    Denmark

    Site Not Available

  • Prehospital Emergency Medical Services, Central Denmark Region

    Aarhus N, 8200
    Denmark

    Active - Recruiting

  • Copenhagen Emergency Medical Services, the Capital Region of Denmark

    Ballerup, 2750
    Denmark

    Site Not Available

  • The Prehospital Center, Region Zealand

    Næstved, 4700
    Denmark

    Site Not Available

  • Emergency Medical Services, the Region of Southern Denmark

    Vejle, 7100
    Denmark

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.