Propolis in Primary Herpetic Gingivostomatitis

Last updated: January 28, 2025
Sponsor: Fayoum University
Overall Status: Completed

Phase

N/A

Condition

Cold Sores (Herpes Labialis Infections)

Treatment

Placebo gel

5% propolis gel

Clinical Study ID

NCT06778655
1212025
  • Ages 3-8
  • All Genders

Study Summary

The purpose of the present study is to investigate the efficacy of 5% propolis gel in the treatment of primary herpetic gingivostomatitis in children and its effect on salivary IFN-γ levels.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • clinical manifestations suggestive of PHGS

  • positive culture for HSV-1

Exclusion

Exclusion Criteria:

  • negative culture for HSV-1

  • allergic to honey or its products

  • patients diagnosed with any systemic diseases, immunosuppressed or immunocompromisedpatients

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: Placebo gel
Phase:
Study Start date:
October 10, 2024
Estimated Completion Date:
January 15, 2025

Connect with a study center

  • fayoum University

    Fayoum,
    Egypt

    Site Not Available

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